Pharming Group N.V.
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Publicatie datum
21 dec 2006 - 07:57
Statutaire naam
Pharming Group N.V.
Titel
DNAGE SCIENTISTS REPORT MAJOR BREAKTHROUGHS IN AGEING RESEARCH - Novel scientific findings published in leading journals
Bericht
Leiden, The Netherlands, December 21, 2006. Biotech company Pharming Group NV (“Pharming” or “the Company”) (Euronext: PHARM) (PHARM.AS) announced today the publication of two important scientific articles in the leading journals Nature and Public Library of Sciences (“PLOS”). These articles describe the work of DNage scientists in the field of aging in collaboration with the Erasmus Medical Center and the University of Pittsburgh. DNage was recently acquired by Pharming and is now a wholly owned subsidiary of the Company.
In the articles the scientists show that accumulation of DNA damage is linked to the development of age-related diseases. While the link between DNA damage and ageing had been established before it has now been shown that the level of “repair-problems” is directly correlated to the severity of the resulting ageing-diseases. The findings indicate that inadequate DNA repair results in accelerated ageing that strongly resembles the processes of natural ageing in older organisms.
Importantly, it was demonstrated that the body activates various natural defence-mechanisms against the accumulation of DNA-damage in order to delay the development of ageing diseases. This indicates that DNA-damage and DNA-repair are very important targets for new products in the field of ageing diseases. Learning from the body’s own response as described by these scientists, the Company is now testing compounds that may eventually lead to products that delay the development of ageing diseases such as Osteoporosis and Neurodegeneration (diseases of the brain including Alzheimer’s and Dementia).
Professor Hoeijmakers, Chief Science Officer of DNage, and senior author of these articles commented: ”Ageing diseases are, apart from their economic and social consequences, amongst the most challenging medical problems in the developed world. The vast majority of the ageing population develops one or more of these diseases at old age which are often difficult to treat. The unders
Datum laatste update: 15 januari 2025